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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPRN
All Species:
29.7
Human Site:
S677
Identified Species:
59.39
UniProt:
Q16849
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16849
NP_002837.1
979
105848
S677
S
S
H
S
S
T
P
S
W
C
E
E
P
A
Q
Chimpanzee
Pan troglodytes
XP_516107
1019
110215
S677
S
S
H
S
S
T
P
S
W
C
E
E
P
A
Q
Rhesus Macaque
Macaca mulatta
XP_001083323
498
55666
D220
M
I
L
S
Y
M
E
D
H
L
K
N
K
N
R
Dog
Lupus familis
XP_536080
1066
115628
S774
S
S
H
S
S
T
P
S
W
C
E
E
P
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q60673
979
106069
S677
S
S
H
S
S
S
P
S
W
C
E
E
P
A
Q
Rat
Rattus norvegicus
Q63259
983
106209
S681
S
S
H
S
S
T
P
S
W
C
E
E
P
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511936
1140
127143
S838
S
A
R
S
S
T
S
S
W
S
E
E
P
V
Q
Chicken
Gallus gallus
XP_418552
1017
113861
S715
S
A
R
S
S
T
S
S
W
C
E
E
P
V
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A4IFW2
1909
213435
H1391
A
N
V
I
A
Y
D
H
S
R
V
V
L
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722672
1306
145632
S915
S
S
R
S
S
T
S
S
W
S
E
E
P
A
L
Honey Bee
Apis mellifera
XP_623773
902
104556
T590
S
S
W
G
E
E
P
T
L
S
N
M
D
I
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789889
533
59466
M254
G
H
V
V
L
S
Y
M
E
D
H
L
N
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.6
34.6
82.8
N.A.
86.9
87.2
N.A.
40.5
41.4
N.A.
20.3
N.A.
29.1
33.4
N.A.
33.4
Protein Similarity:
100
93.2
42
85.6
N.A.
90.8
91.1
N.A.
54.2
55.8
N.A.
31
N.A.
42.2
47.4
N.A.
44
P-Site Identity:
100
100
6.6
100
N.A.
93.3
100
N.A.
66.6
73.3
N.A.
0
N.A.
73.3
20
N.A.
0
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
73.3
80
N.A.
20
N.A.
73.3
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
0
0
9
0
0
0
0
0
0
0
0
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
9
0
9
0
0
9
0
0
% D
% Glu:
0
0
0
0
9
9
9
0
9
0
67
67
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
9
42
0
0
0
0
9
9
0
9
0
0
0
0
% H
% Ile:
0
9
0
9
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
9
% K
% Leu:
0
0
9
0
9
0
0
0
9
9
0
9
9
0
9
% L
% Met:
9
0
0
0
0
9
0
9
0
0
0
9
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
9
9
9
17
0
% N
% Pro:
0
0
0
0
0
0
50
0
0
0
0
0
67
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
59
% Q
% Arg:
0
0
25
0
0
0
0
0
0
9
0
0
0
0
9
% R
% Ser:
75
59
0
75
67
17
25
67
9
25
0
0
0
0
9
% S
% Thr:
0
0
0
0
0
59
0
9
0
0
0
0
0
9
0
% T
% Val:
0
0
17
9
0
0
0
0
0
0
9
9
0
17
0
% V
% Trp:
0
0
9
0
0
0
0
0
67
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
9
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _